Question:
After a year and a half of university hell, I finally saw a psychiatrist and started treatment for ADHD—and, like many of you have probably experienced, it was like a giant lightbulb went on over my life.
For the first time I could listen to entire lectures, take reading notes, manage my finances, avoid constant guilt/anxiety over being chronically scattered, remember appointments, keep my apartment organized...etc.
World-changing. Then, yesterday, my pharmacist noticed that Adderall is contraindicated in patients with glaucoma, which I have.
Long story short, he called my doctor, and my doctor called me and told me to stop taking the meds—without offering any alternatives. So now I am in the MADDENING position of knowing how beautiful it is to be able to function like a normal human being...and having that all fall apart.
Now I am looking forward to...I'm not even sure.
I don't think I could stand to go back to the way I was, knowing what it feels like to be medicated.
I spent today trying to study, failing, crying out of frustration, trying again, etc.
Not pretty. So, I guess my plea for help is: if you know of any fast-acting non-stimulant treatments for ADHD, please share!
(Strattera etc. may be options but I would really like something I can start using in the next few days...graaah midterm season!) Alternatively, if anyone else out there has glaucoma and ADHD and has figured out a way to counteract the IOP-increasing effect of the stimulant meds, or found other successful treatments...please let me know!
Answer:
Talk to your eye doctor and see if he is treating patients on ADHD meds.
ADHD meds can make a hypertensives BP skyrocket (or anyones) but BP meds can be adjusted for that.
Seems the same logic may apply to glaucoma.
Your eye doctor would be able to say for sure.
He could then contact your ADHD doctor if its possible for you.
If your eye doctor has no experience in the matter seek another eye doctors advice.
Answer:
I would first consult a Ophthalmologist and see what possible problems you could have in the future.
Low dose beta-blocker is your best bet for cutting the peripheral stim effects of the adderall....keep dialogue open between you and doctor.
He should be the one looking for a solution not you. Keep us posted
Answer
Thanks for the replies, both of you!
I'm currently waiting to see a new psychiatrist (the medication incident coincided with me deciding to switch doctors, so there's about a week of downtime) so I can get a referral for an ophthalmologist and also look at other treatment options.
Not much of an update, I'm afraid.
(:
Answer:
Sansserifs, That is really rum luck about the medication.
One thing that can still be very helpful is aerobic exercise multiple times a day.
Dr. John Ratey in his book Spark and Delivered from Distraction discusses how exercise can act like a dose of Adderall and Prozac combined in increasing the levels of dopamine and serotonin.
Guys should aim for 75% or their maximum heart rate and gals for 65% for optimum focus.
Think of it a bit like short acting Ritalin -- the first hour is the golden one and the effects of improved focus can last from 2 - 4 hours depending on the person.
Even just a 10 minute burst of exercise can help the brain get back down to business.
That's definately how I got through college (back in the dark ages without medication) -- lots of running, climbing stairs, and pacing the halls.
It's especially helpful if you're getting enough Omega III fatty acids to build the neurotransmitters the exercise stimulates. Other wholistic helpers include reducing the amount of refined food which immediately turns to sugar in your system causing your insulin to spike and then drop quickly leaving your brain with less glucose (the ADD brain already battles that issue in the frontal lobes) and music can also help stimulate the brain. I hope you can find a medication that is helpful without worsening your glaucoma, but in the mean time -- go for a jog or brisk walk before those mid-terms or while studying for them -- it'll help!
Answer:
Wellbutrin might be worth a try?
It takes 3 weeks to start working, but I found it quite helpful.
Answer
First, let me start off by saying that have not tried ADHD drug bifemelane .
However, I have seen some good things about its potential use for ADHD, Parkinson's, autism, dementia, memory loss, and even some mood disorders.
It's definitely a versatile drug!
However, I also read that bifemelane has actually been suggested as a possible treatment for glaucoma . I don't know a whole lot more about this drug bifemelane at the moment, but if you are concerned about glaucoma, this sounds like something you might want to check into.
Good luck! Quote: : Alternatively, if anyone else out there has glaucoma and ADHD and has figured out a way to counteract the IOP-increasing effect of the stimulant meds, or found other successful treatments...please let me know!
Answer:
Quote: : Talk to your eye doctor and see if he is treating patients on ADHD meds.
ADHD meds can make a hypertensives BP skyrocket (or anyones) but BP meds can be adjusted for that.
Seems the same logic may apply to glaucoma.
Your eye doctor would be able to say for sure.
He could then contact your ADHD doctor if its possible for you.
If your eye doctor has no experience in the matter seek another eye doctors advice.
I just discovered how bad Adderall is for people with Glaucoma.
To be honest, I won't be going back to my doctor.
The only time her name will be coming out of my mouth is when I have the opportunity to make sure she has a bad name.
Right now I don't think I want my Glaucoma specialists talking to my doctor, shes ignorant and hes not much of a people person so that could be bad for everyone involved. Quote: : So now I am in the MADDENING position of knowing how beautiful it is to be able to function like a normal human being...and having that all fall apart.
Now I am looking forward to...I'm not even sure.
I don't think I could stand to go back to the way I was, knowing what it feels like to be medicated.
I spent today trying to study, failing, crying out of frustration, trying again, etc.
Not pretty. What a tease huh?
I know how you feel, at least your doctor gave you a call and your pharmacist noticed it.
I found out after looking at Adderall on drugs.com, I was planning out a diet and thought I'd make check to see if it said to avoid or include anything specific.
I'll be calling my Eye Doctor tomorrow for some info, probably finding a new doctor as I would recommend you do as well, and letting my previous know what I think.
I really can't beleive that the pharmicist didn't catch this, my stuff is usually filled through the techs and the one time the actual pharmicists fills mine its complete fail. I don't know what your whole take is on the situation.
I feel pretty teased, really foolish and I've really been questioning my judgement.
I've gone to this doctor for some time, she seemed ok and all that trust for her and the profession is gone.
Above all else, I have this massive amount of anger, the last 40 hours or so the smallest little frustrations have been sending me through the roof.
I'm the type of person thats usually really calm, rarely ever gets mad..
But when I do.. no one wants to be around and I'm smart enough to seperate myself from the situation.
Kind of hard in this scenerio though. Let me know what you find out, I'll post my findings as well.
Answer:
I struggle with ADHD and depression, also have glaucoma.
Does Bifemelane have a brand name.
I'd appreciate further suggestions on meds that don't up IOP.
Blindness vs. brain dead, some choice.
Saturday, November 7, 2009
Can sinusitis/inflamation cause high IOP?
no. not usually.
there are limited number of new questions on this website per day. if you have multiple questions pertaining to the same or similar complaints, please post them in the 1 thread you already started instead of starting a new thread. this will keep others from being denied asking their question b/c the daily quota had been filled...just for future reference :)
there are limited number of new questions on this website per day. if you have multiple questions pertaining to the same or similar complaints, please post them in the 1 thread you already started instead of starting a new thread. this will keep others from being denied asking their question b/c the daily quota had been filled...just for future reference :)
Glaucoma Alternative Medicine ? - discussion in the Drugs.com community
Question
Hello folks ... This is my first post ( new herein ) I suffered from glaucoma since 2003 January looking forward to hearing remedies of natural type ... not medicinal droplets ... Thanks and cheers ... [B)][:I][?] There are no strangers in this world, only friends waiting to be met and made
Reply:
Have you already looked at glaucoma from the psychosomatic point of view?
Reply:
Marijuana is just a dried plant from the ground.
No additives, no mechanical processing, just a little smelly plant.
Eat it. Jesus Christ will help you through.
-Betsy
Hello folks ... This is my first post ( new herein ) I suffered from glaucoma since 2003 January looking forward to hearing remedies of natural type ... not medicinal droplets ... Thanks and cheers ... [B)][:I][?] There are no strangers in this world, only friends waiting to be met and made
Reply:
Have you already looked at glaucoma from the psychosomatic point of view?
Reply:
Marijuana is just a dried plant from the ground.
No additives, no mechanical processing, just a little smelly plant.
Eat it. Jesus Christ will help you through.
-Betsy
Diabetes and Glaucoma optometric pearls
Diabetes and Glaucoma optometric pearls | Optometry | Student Doctor Network
I made a blog entry about different pearls for the management of glaucoma and diabetic retinopathy patients, and I thought that it would be nice to share them.
Here they are: Diabetics: Ask what the patient's last blood glucose (particularly fasting) and HbA1c were.
Ask if it has been under good control.
These numbers are super helpful with predicting the likelihood of diabetic retinopathy, or how bad it is if they have it.
Ask how long the patient has had diabetes.
It is well recorded in the literature that the longer the patient has had diabetes, the higher the risk for retinopathy.
According to the American Diabetes Association, 10% of those who had been diagnosed for less than 5 years had retinopathy, 39% for those diagnosed 5-14 yrs, and a whopping 70% for those diagnosed for more than 15 years.
Record the pertinent negatives.
What does this mean?
Basically, record the main things that we check for in the eye for diabetics: check carefully for neovascularization of the iris, disc, and elsewhere (NVI, NVD, and NVE, respectively).
Also, check for clinically significant macular edema (CSME).
In other words, if you didn't see any of these signs, record "no NVI, NVD, NVE, CSME" Glaucoma: For glaucoma patients on medication, it's important to ask specific questions about compliance;
Don't simply ask "are you good with taking your drops?".
Ask them when they last took their medication.
Also ask them how often they forget their drops, if they do at all.
These questions are important for you to determine if the IOP that you're taking is falsely high or not, or if you're wondering why there are more defects in the threshold visual field test you just took.
It is not uncommon for glaucoma patients to be poor with compliance, especially if their vision is good and there is no immediate risk to vision loss.
Remember that suspicions for glaucoma are raised with race (especially African Americans) and a history of glaucoma in the family (in addition to your optic nerve head evaluation, threshold visual fields result, etc).
Make sure to take note of these facts in your assessment.
For every diagnosis of glaucoma, it is important to do gonioscopy.
In order to truly diagnose an open angle glaucoma, you must rule out other causes of glaucoma e.g.
Pigmentary dispersion, etc.
I'd love to hear of your own optometric pearls, and they don't have to be about glaucoma or DR.
If this post gets enough replies, I'd like to make a web page full of selected pearls, with your permission and due credit of course!
Thanks in advance, your contribution would benefit many!
Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same. 2.
Lumigan tends to lower IOP better than Travatan, which lowers IOP better than Xalatan. 3.
Lumigan is usually associated with the most conjunctival hyperemia, so I don't usually start Lumigan as first line therapy.
If a patient is using another prostaglandin analogue (Travatan or Xalatan), this tends to "prep" the eye and it will not be as hyperemic after switching to Lumigan later on. 4.
Azopt tends to be the best secondary agent when combined with a Prostaglandin analogue.
This is when compared to other drops like Alphagan or a beta blocker. 5.
Alphagan (and Combigan) can cause systemic sedation.
Patients may feel "tired or sleepy" when using these eye drops.
Make sure you instruct them to do punctal occlusion after drop instillation. 6.
Pseudoexfoliative glaucoma responds best to a beta blocker, followed by Prostaglandin 7.
I've heard that IOP is highest at 2am, is this true?!? I'll update this post if I think of anything else.
This attached lecture is an excellent evidence based review of treatment options. Also, in my experience Alphagan is my preference as a secondary/additive agent.
Quote: : Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same.
Lumigan (bimatoprost) is a prostamide, and the other prostaglandin analogues are not.
A good way to remember that: bimatoprost isn't as potent, so this is why Lumigan's drug concentration is 0.03%, where the others are 0.004% (Travatan) and 0.005% (Xalatan).
Quote: : 7. I've heard that IOP is highest at 2am, is this true?!? We've been taught it is highest right before waking up, around 5-6 am for normal schedule sleepers.
So 2,5,6 am, whatever, sometime early morning Oh, and if someone for example works the night shift, their IOP peak won't be the same time, it will change based on their sleep schedule.
Quote: : Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same. 2.
Lumigan tends to lower IOP better than Travatan, which lowers IOP better than Xalatan. 3.
Lumigan is usually associated with the most conjunctival hyperemia, so I don't usually start Lumigan as first line therapy.
If a patient is using another prostaglandin analogue (Travatan or Xalatan), this tends to "prep" the eye and it will not be as hyperemic after switching to Lumigan later on. 4.
Azopt tends to be the best secondary agent when combined with a Prostaglandin analogue.
This is when compared to other drops like Alphagan or a beta blocker. 5.
Alphagan (and Combigan) can cause systemic sedation.
Patients may feel "tired or sleepy" when using these eye drops.
Make sure you instruct them to do punctal occlusion after drop instillation. 6.
Pseudoexfoliative glaucoma responds best to a beta blocker, followed by Prostaglandin 7.
I've heard that IOP is highest at 2am, is this true?!? I'll update this post if I think of anything else.
A couple of thoughts: On the prostaglandins: don't go straight for the "if the Xalatan doesn't work well, go with Travatan" try to know the reasons.
Studies are showing that Travatan works better in black patients than Xalatan. Lumigan causes less of the hyperpigmentation problems with the other 2, less headaches (as symptoms ) but will give more conj hyperemia. Also, recent, recent studies and discussions in glaucoma are moving away from "whichever lowers IOP best" when you can have a low IOP but still have NFL loss.
Some studies are recommending for newly diagnosis, use a prostaglandin to get the IOP controlled, then transfer to a Alphagan- as it is a neuroprotectant.
I encourage everyone to read new literature on neuroprotectants. Jack Kanski (love him) has listed several items of interest to prescribe: Betaxolol, Alphagan, Vit E, and Ginko Biloba.
These items have nueroprotective qualities to them, with the drugs having proved VF saving results. This explains renewed interest in some poly glaucoma drugs as they are incorporating a proven IOP lowering substane with a paired nueroprotectant. Please research this! Good luck everybody!
Quote: : courage everyone to read new literature on neuroprotectants. Jack Kanski (love him) has listed several items of interest to prescribe: Betaxolol, Alphagan, Vit E, and Ginko Biloba.
These items have nueroprotective qualities to them, with the drugs having proved VF saving results. This explains renewed interest in some poly glaucoma drugs as they are incorporating a proven IOP lowering substane with a paired nueroprotectant.
Any relevant articles on this?
My understanding is that the whole "neuroprotection" thing is still very much just speculation without any solid research behind it...
Quote: : Any relevant articles on this?
My understanding is that the whole "neuroprotection" thing is still very much just speculation without any solid research behind it...
There are about 10 years of studies done on Timolol vs Brimonidine showing that Timolol does keep the IOP lower, but visual field continues to restrict over the years, while Brimonidine does not lower IOP as much, yet visual field is preserved.
Betaxolol is also showing this preservation of the VF. This is why I said Alphagan is quickly becoming a preferred polypharmacy with a Beta Blocker or Prostaglandin. Its not a bunch of hocus pocus--- unless someone claims to know HOW this works.
That is not yet certain. I'll repost tomorrow concerning the articles for those wanting to read this info for themselves.
Quote: : There are about 10 years of studies done on Timolol vs Brimonidine showing that Timolol does keep the IOP lower, but visual field continues to restrict over the years, while Brimonidine does not lower IOP as much, yet visual field is preserved.
Betaxolol is also showing this preservation of the VF. This is why I said Alphagan is quickly becoming a preferred polypharmacy with a Beta Blocker or Prostaglandin. Its not a bunch of hocus pocus--- unless someone claims to know HOW this works.
That is not yet certain. I'll repost tomorrow concerning the articles for those wanting to read this info for themselves.
I agree, brimonidine is my preferred agent for adjunctive therapy, but I think they're still plenty of work left to prove this neuroprotection thing.
Info can be found in: Glaucoma, by Jack Kanski: http://www.amazon.com/Glaucoma-Jack-...4873501&sr=8-1 articles: http://www.pubmedcentral.nih.gov/art...?artid=1936355 I have two more, but cannot find them for some reason. The research started about 1999, and is continuing.
Also, this nuero-protection stuff seems to be hocus-pocus when discussed regarding Parkingsons, but the glaucoma test-trails are promising. thanks for the interest.
Quote: : I agree, brimonidine is my preferred agent for adjunctive therapy, but I think they're still plenty of work left to prove this neuroprotection thing.
I just returned from vision expo and the consensus was that the whole "neuro protection" thing was such a titanic failure that Allergan shelved the entire thing after spending $65 million.
I made a blog entry about different pearls for the management of glaucoma and diabetic retinopathy patients, and I thought that it would be nice to share them.
Here they are: Diabetics: Ask what the patient's last blood glucose (particularly fasting) and HbA1c were.
Ask if it has been under good control.
These numbers are super helpful with predicting the likelihood of diabetic retinopathy, or how bad it is if they have it.
Ask how long the patient has had diabetes.
It is well recorded in the literature that the longer the patient has had diabetes, the higher the risk for retinopathy.
According to the American Diabetes Association, 10% of those who had been diagnosed for less than 5 years had retinopathy, 39% for those diagnosed 5-14 yrs, and a whopping 70% for those diagnosed for more than 15 years.
Record the pertinent negatives.
What does this mean?
Basically, record the main things that we check for in the eye for diabetics: check carefully for neovascularization of the iris, disc, and elsewhere (NVI, NVD, and NVE, respectively).
Also, check for clinically significant macular edema (CSME).
In other words, if you didn't see any of these signs, record "no NVI, NVD, NVE, CSME" Glaucoma: For glaucoma patients on medication, it's important to ask specific questions about compliance;
Don't simply ask "are you good with taking your drops?".
Ask them when they last took their medication.
Also ask them how often they forget their drops, if they do at all.
These questions are important for you to determine if the IOP that you're taking is falsely high or not, or if you're wondering why there are more defects in the threshold visual field test you just took.
It is not uncommon for glaucoma patients to be poor with compliance, especially if their vision is good and there is no immediate risk to vision loss.
Remember that suspicions for glaucoma are raised with race (especially African Americans) and a history of glaucoma in the family (in addition to your optic nerve head evaluation, threshold visual fields result, etc).
Make sure to take note of these facts in your assessment.
For every diagnosis of glaucoma, it is important to do gonioscopy.
In order to truly diagnose an open angle glaucoma, you must rule out other causes of glaucoma e.g.
Pigmentary dispersion, etc.
I'd love to hear of your own optometric pearls, and they don't have to be about glaucoma or DR.
If this post gets enough replies, I'd like to make a web page full of selected pearls, with your permission and due credit of course!
Thanks in advance, your contribution would benefit many!
Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same. 2.
Lumigan tends to lower IOP better than Travatan, which lowers IOP better than Xalatan. 3.
Lumigan is usually associated with the most conjunctival hyperemia, so I don't usually start Lumigan as first line therapy.
If a patient is using another prostaglandin analogue (Travatan or Xalatan), this tends to "prep" the eye and it will not be as hyperemic after switching to Lumigan later on. 4.
Azopt tends to be the best secondary agent when combined with a Prostaglandin analogue.
This is when compared to other drops like Alphagan or a beta blocker. 5.
Alphagan (and Combigan) can cause systemic sedation.
Patients may feel "tired or sleepy" when using these eye drops.
Make sure you instruct them to do punctal occlusion after drop instillation. 6.
Pseudoexfoliative glaucoma responds best to a beta blocker, followed by Prostaglandin 7.
I've heard that IOP is highest at 2am, is this true?!? I'll update this post if I think of anything else.
This attached lecture is an excellent evidence based review of treatment options. Also, in my experience Alphagan is my preference as a secondary/additive agent.
Quote: : Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same.
Lumigan (bimatoprost) is a prostamide, and the other prostaglandin analogues are not.
A good way to remember that: bimatoprost isn't as potent, so this is why Lumigan's drug concentration is 0.03%, where the others are 0.004% (Travatan) and 0.005% (Xalatan).
Quote: : 7. I've heard that IOP is highest at 2am, is this true?!? We've been taught it is highest right before waking up, around 5-6 am for normal schedule sleepers.
So 2,5,6 am, whatever, sometime early morning Oh, and if someone for example works the night shift, their IOP peak won't be the same time, it will change based on their sleep schedule.
Quote: : Correct me if anyone disagrees, but this is what I've read and also have experienced regarding glaucoma therapy: 1.
Travatan and Xalatan fall under the same mechanism of action as prostaglandin analogues, versus Lumigan, which is a prostaglandin analogue that works slightly differently.
I forget the reason, someone here may know.
Therefore, if you are currently using Travatan but it is not working well, consider switching to Lumigan instead of Xalatan, since they work the same. 2.
Lumigan tends to lower IOP better than Travatan, which lowers IOP better than Xalatan. 3.
Lumigan is usually associated with the most conjunctival hyperemia, so I don't usually start Lumigan as first line therapy.
If a patient is using another prostaglandin analogue (Travatan or Xalatan), this tends to "prep" the eye and it will not be as hyperemic after switching to Lumigan later on. 4.
Azopt tends to be the best secondary agent when combined with a Prostaglandin analogue.
This is when compared to other drops like Alphagan or a beta blocker. 5.
Alphagan (and Combigan) can cause systemic sedation.
Patients may feel "tired or sleepy" when using these eye drops.
Make sure you instruct them to do punctal occlusion after drop instillation. 6.
Pseudoexfoliative glaucoma responds best to a beta blocker, followed by Prostaglandin 7.
I've heard that IOP is highest at 2am, is this true?!? I'll update this post if I think of anything else.
A couple of thoughts: On the prostaglandins: don't go straight for the "if the Xalatan doesn't work well, go with Travatan" try to know the reasons.
Studies are showing that Travatan works better in black patients than Xalatan. Lumigan causes less of the hyperpigmentation problems with the other 2, less headaches (as symptoms ) but will give more conj hyperemia. Also, recent, recent studies and discussions in glaucoma are moving away from "whichever lowers IOP best" when you can have a low IOP but still have NFL loss.
Some studies are recommending for newly diagnosis, use a prostaglandin to get the IOP controlled, then transfer to a Alphagan- as it is a neuroprotectant.
I encourage everyone to read new literature on neuroprotectants. Jack Kanski (love him) has listed several items of interest to prescribe: Betaxolol, Alphagan, Vit E, and Ginko Biloba.
These items have nueroprotective qualities to them, with the drugs having proved VF saving results. This explains renewed interest in some poly glaucoma drugs as they are incorporating a proven IOP lowering substane with a paired nueroprotectant. Please research this! Good luck everybody!
Quote: : courage everyone to read new literature on neuroprotectants. Jack Kanski (love him) has listed several items of interest to prescribe: Betaxolol, Alphagan, Vit E, and Ginko Biloba.
These items have nueroprotective qualities to them, with the drugs having proved VF saving results. This explains renewed interest in some poly glaucoma drugs as they are incorporating a proven IOP lowering substane with a paired nueroprotectant.
Any relevant articles on this?
My understanding is that the whole "neuroprotection" thing is still very much just speculation without any solid research behind it...
Quote: : Any relevant articles on this?
My understanding is that the whole "neuroprotection" thing is still very much just speculation without any solid research behind it...
There are about 10 years of studies done on Timolol vs Brimonidine showing that Timolol does keep the IOP lower, but visual field continues to restrict over the years, while Brimonidine does not lower IOP as much, yet visual field is preserved.
Betaxolol is also showing this preservation of the VF. This is why I said Alphagan is quickly becoming a preferred polypharmacy with a Beta Blocker or Prostaglandin. Its not a bunch of hocus pocus--- unless someone claims to know HOW this works.
That is not yet certain. I'll repost tomorrow concerning the articles for those wanting to read this info for themselves.
Quote: : There are about 10 years of studies done on Timolol vs Brimonidine showing that Timolol does keep the IOP lower, but visual field continues to restrict over the years, while Brimonidine does not lower IOP as much, yet visual field is preserved.
Betaxolol is also showing this preservation of the VF. This is why I said Alphagan is quickly becoming a preferred polypharmacy with a Beta Blocker or Prostaglandin. Its not a bunch of hocus pocus--- unless someone claims to know HOW this works.
That is not yet certain. I'll repost tomorrow concerning the articles for those wanting to read this info for themselves.
I agree, brimonidine is my preferred agent for adjunctive therapy, but I think they're still plenty of work left to prove this neuroprotection thing.
Info can be found in: Glaucoma, by Jack Kanski: http://www.amazon.com/Glaucoma-Jack-...4873501&sr=8-1 articles: http://www.pubmedcentral.nih.gov/art...?artid=1936355 I have two more, but cannot find them for some reason. The research started about 1999, and is continuing.
Also, this nuero-protection stuff seems to be hocus-pocus when discussed regarding Parkingsons, but the glaucoma test-trails are promising. thanks for the interest.
Quote: : I agree, brimonidine is my preferred agent for adjunctive therapy, but I think they're still plenty of work left to prove this neuroprotection thing.
I just returned from vision expo and the consensus was that the whole "neuro protection" thing was such a titanic failure that Allergan shelved the entire thing after spending $65 million.
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